| 1 | Mission: Impossible II (Paramount) | $317,319,000 | $85,213,000 | $28,404,000 | May 24, 2000 |
| 2 | How the Grinch Stole Christmas (Universal) | $383,071,000 | $81,142,000 | $27,047,000 | Nov 17, 2000 |
| 3 | X-Men (Fox) | $231,717,000 | $80,243,000 | $26,748,000 | Jul 14, 2000 |
| 4 | Nutty Professor II: The Klumps (Universal) | $181,647,000 | $62,633,000 | $20,878,000 | Jul 28, 2000 |
| 5 | Scary Movie (Miramax / Dimension) | $231,305,000 | $62,381,000 | $20,794,000 | Jul 07, 2000 |
| 6 | The Perfect Storm (Warner Bros.) | $269,014,000 | $60,879,000 | $20,293,000 | Jun 30, 2000 |
| 7 | Charlie's Angels (Sony / Columbia) | $184,587,000 | $59,114,000 | $19,705,000 | Nov 03, 2000 |
| 8 | Dinosaur (Disney) | $202,917,000 | $57,237,000 | $19,079,000 | May 19, 2000 |
| 9 | Gladiator (2000) (DreamWorks) | $276,509,000 | $51,292,000 | $17,097,000 | May 05, 2000 |
| 10 | Scream 3 (Miramax / Dimension) | $131,317,000 | $51,136,000 | $17,045,000 | Feb 04, 2000 |
| 11 | What Women Want (2000) (Paramount) | $269,300,000 | $49,518,000 | $16,506,000 | Dec 15, 2000 |
| 12 | Unbreakable (Disney) | $139,961,000 | $44,682,000 | $14,894,000 | Nov 22, 2000 |
| 13 | What Lies Beneath (DreamWorks) | $229,008,000 | $43,756,000 | $14,585,000 | Jul 21, 2000 |
| 14 | Cast Away (Fox) | $344,163,000 | $42,550,000 | $14,183,000 | Dec 22, 2000 |
| 15 | Meet the Parents (Universal) | $244,895,000 | $42,164,000 | $14,055,000 | Oct 06, 2000 |
| 16 | Erin Brockovich (Universal) | $185,015,000 | $41,451,000 | $13,817,000 | Mar 17, 2000 |
| 17 | Hollow Man (Sony / Columbia) | $107,845,000 | $38,911,000 | $12,970,000 | Aug 04, 2000 |
| 18 | Big Momma's House (Fox) | $173,176,000 | $37,799,000 | $12,600,000 | Jun 02, 2000 |
| 19 | Gone in 60 Seconds (Disney) | $149,738,000 | $37,322,000 | $12,441,000 | Jun 09, 2000 |
| 20 | Me, Myself & Irene (Fox) | $133,419,000 | $35,663,000 | $11,888,000 | Jun 23, 2000 |
| 21 | Mission to Mars (Disney) | $89,687,000 | $33,668,000 | $11,223,000 | Mar 10, 2000 |
| 22 | Rugrats in Paris: The Movie (Paramount) | $112,703,000 | $33,466,000 | $11,155,000 | Nov 17, 2000 |
| 23 | The Patriot (Sony / Columbia) | $166,947,000 | $33,018,000 | $11,006,000 | Jun 28, 2000 |
| 24 | Shaft (Paramount) | $103,610,000 | $31,988,000 | $10,663,000 | Jun 16, 2000 |
| 25 | Remember the Titans (Disney) | $170,370,000 | $30,796,000 | $10,265,000 | Sep 29, 2000 |
| 26 | 102 Dalmatians (Disney) | $98,636,000 | $29,292,000 | $9,764,000 | Nov 22, 2000 |
| 27 | Pokemon: The Movie 2000 (Warner Bros.) | $64,460,000 | $28,837,000 | $9,612,000 | Jul 21, 2000 |
| 28 | U-571 (Universal) | $113,609,000 | $28,804,000 | $9,601,000 | Apr 21, 2000 |
| 29 | Space Cowboys (Warner Bros.) | $133,264,000 | $26,654,000 | $8,885,000 | Aug 04, 2000 |
| 30 | Romeo Must Die (Warner Bros.) | $82,455,000 | $26,537,000 | $8,846,000 | Mar 22, 2000 |
| 31 | The Cell (New Line) | $90,351,000 | $25,801,000 | $8,600,000 | Aug 18, 2000 |
| 32 | Chicken Run (DreamWorks) | $157,377,000 | $25,788,000 | $8,596,000 | Jun 21, 2000 |
| 33 | Bring It On (Universal) | $100,729,000 | $25,574,000 | $8,525,000 | Aug 25, 2000 |
| 34 | Coyote Ugly (Disney) | $89,544,000 | $25,513,000 | $8,504,000 | Aug 04, 2000 |
| 35 | Little Nicky (New Line) | $58,136,000 | $23,664,000 | $7,888,000 | Nov 10, 2000 |
| 36 | Hanging Up (Sony / Columbia) | $53,105,000 | $23,143,000 | $7,714,000 | Feb 18, 2000 |
| 37 | Shanghai Noon (Disney) | $83,874,000 | $22,991,000 | $7,664,000 | May 26, 2000 |
| 38 | Traffic (USA Films) | $182,835,000 | $22,861,000 | $7,620,000 | Dec 27, 2000 |
| 39 | Vertical Limit (Sony / Columbia) | $102,002,000 | $22,845,000 | $7,615,000 | Dec 08, 2000 |
| 40 | Road Trip (DreamWorks) | $100,967,000 | $22,811,000 | $7,604,000 | May 19, 2000 |
| 41 | The Beach (Fox) | $58,608,000 | $22,506,000 | $7,502,000 | Feb 11, 2000 |
| 42 | The Family Man (Universal) | $111,651,000 | $22,250,000 | $7,417,000 | Dec 22, 2000 |
| 43 | Rules of Engagement (Paramount) | $90,353,000 | $22,113,000 | $7,371,000 | Apr 07, 2000 |
| 44 | Next Friday (New Line) | $84,451,000 | $21,347,000 | $7,116,000 | Jan 12, 2000 |
| 45 | Snow Day (Paramount) | $88,416,000 | $21,112,000 | $7,037,000 | Feb 11, 2000 |
| 46 | Miss Congeniality (Warner Bros.) | $157,337,000 | $20,408,000 | $6,803,000 | Dec 22, 2000 |
| 47 | Dude, Where's My Car? (Fox) | $68,837,000 | $20,396,000 | $6,799,000 | Dec 15, 2000 |
| 48 | The Whole Nine Yards (Warner Bros.) | $84,353,000 | $20,229,000 | $6,743,000 | Feb 18, 2000 |
| 49 | Men of Honor (Fox) | $71,914,000 | $19,650,000 | $6,550,000 | Nov 10, 2000 |
| 50 | Book of Shadows: Blair Witch 2 (Artisan) | $38,945,000 | $19,480,000 | $6,493,000 | Oct 27, 2000 |
| 51 | Bedazzled (2000) (Fox) | $55,811,000 | $19,307,000 | $6,436,000 | Oct 20, 2000 |
| 52 | The 6th Day (Sony / Columbia) | $50,976,000 | $19,182,000 | $6,394,000 | Nov 17, 2000 |
| 53 | The Road to El Dorado (DreamWorks) | $74,926,000 | $18,924,000 | $6,308,000 | Mar 31, 2000 |
| 54 | Disney's The Kid (Disney) | $102,663,000 | $18,690,000 | $6,230,000 | Jul 07, 2000 |
| 55 | Pitch Black (USA Films) | $57,805,000 | $17,138,000 | $5,713,000 | Feb 18, 2000 |
| 56 | Battlefield Earth (Warner Bros.) | $31,630,000 | $17,013,000 | $5,671,000 | May 12, 2000 |
| 57 | The Legend of Bagger Vance (DreamWorks) | $45,548,000 | $16,965,000 | $5,655,000 | Nov 03, 2000 |
| 58 | Bounce (Miramax) | $54,218,000 | $16,828,000 | $5,609,000 | Nov 17, 2000 |
| 59 | The Original Kings of Comedy (Paramount) | $56,246,000 | $16,283,000 | $5,428,000 | Aug 18, 2000 |
| 60 | The Replacements (Warner Bros.) | $65,903,000 | $16,262,000 | $5,421,000 | Aug 11, 2000 |
| 61 | The Skulls (Universal) | $51,626,000 | $16,258,000 | $5,419,000 | Mar 31, 2000 |
| 62 | Autumn in New York (MGM) | $55,627,000 | $16,185,000 | $5,395,000 | Aug 11, 2000 |
| 63 | The Flintstones in Viva Rock Vegas (Universal) | $51,955,000 | $15,494,000 | $5,165,000 | Apr 28, 2000 |
| 64 | The Art of War (Warner Bros.) | $44,501,000 | $15,336,000 | $5,112,000 | Aug 25, 2000 |
| 65 | 28 Days (Sony / Columbia) | $54,755,000 | $15,189,000 | $5,063,000 | Apr 14, 2000 |
| 66 | Proof of Life (Warner Bros.) | $48,020,000 | $15,037,000 | $5,012,000 | Dec 08, 2000 |
| 67 | Final Destination (New Line) | $78,563,000 | $14,754,000 | $4,918,000 | Mar 17, 2000 |
| 68 | The Emperor's New Groove (Disney) | $131,551,000 | $14,454,000 | $4,818,000 | Dec 15, 2000 |
| 69 | Thirteen Days (New Line) | $50,958,000 | $14,391,000 | $4,797,000 | Dec 25, 2000 |
| 70 | Pay It Forward (Warner Bros.) | $49,377,000 | $14,188,000 | $4,729,000 | Oct 20, 2000 |
| 71 | The Tigger Movie (Disney) | $67,106,000 | $13,887,000 | $4,629,000 | Feb 11, 2000 |
| 72 | Bless the Child (Paramount) | $43,281,000 | $13,867,000 | $4,622,000 | Aug 11, 2000 |
| 73 | Titan A.E. (Fox) | $33,518,000 | $13,813,000 | $4,604,000 | Jun 16, 2000 |
| 74 | The Watcher (Universal) | $42,642,000 | $13,351,000 | $4,450,000 | Sep 08, 2000 |
| 75 | Frequency (New Line) | $66,304,000 | $13,296,000 | $4,432,000 | Apr 28, 2000 |
| 76 | Red Planet (Warner Bros.) | $25,751,000 | $12,847,000 | $4,282,000 | Nov 10, 2000 |
| 77 | Dracula 2000 (Miramax / Dimension) | $48,645,000 | $12,723,000 | $4,241,000 | Dec 22, 2000 |
| 78 | Urban Legends: Final Cut (Sony / Columbia) | $31,625,000 | $12,529,000 | $4,176,000 | Sep 22, 2000 |
| 79 | Where the Heart Is (Fox) | $49,749,000 | $12,216,000 | $4,072,000 | Apr 28, 2000 |
| 80 | The Exorcist: The Version You've Never Seen (Warner Bros.) | $58,440,000 | $12,044,000 | $4,015,000 | Sep 22, 2000 |
| 81 | Love & Basketball (New Line) | $40,451,000 | $11,990,000 | $3,997,000 | Apr 21, 2000 |
| 82 | Reindeer Games (Miramax / Dimension) | $34,425,000 | $11,974,000 | $3,991,000 | Feb 25, 2000 |
| 83 | Keeping the Faith (Disney) | $54,574,000 | $11,901,000 | $3,967,000 | Apr 14, 2000 |
| 84 | Lost Souls (New Line) | $24,771,000 | $11,718,000 | $3,906,000 | Oct 13, 2000 |
| 85 | Return to Me (MGM) | $48,203,000 | $11,521,000 | $3,840,000 | Apr 07, 2000 |
| 86 | Down to You (Miramax) | $29,565,000 | $11,199,000 | $3,733,000 | Jan 21, 2000 |
| 87 | Dungeons & Dragons (New Line) | $22,422,000 | $10,661,000 | $3,554,000 | Dec 08, 2000 |
| 88 | Nurse Betty (USA Films) | $37,079,000 | $10,527,000 | $3,509,000 | Sep 08, 2000 |
| 89 | Boys and Girls (Miramax / Dimension) | $32,113,000 | $10,325,000 | $3,442,000 | Jun 16, 2000 |
| 90 | The Adventures of Rocky & Bullwinkle (Universal) | $38,308,000 | $10,038,000 | $3,346,000 | Jun 30, 2000 |
| 91 | Supernova (MGM) | $20,963,000 | $9,917,000 | $3,306,000 | Jan 14, 2000 |
| 92 | Boiler Room (New Line) | $25,000,000 | $9,903,000 | $3,301,000 | Feb 18, 2000 |
| 93 | Get Carter (Warner Bros.) | $22,048,000 | $9,778,000 | $3,259,000 | Oct 06, 2000 |
| 94 | The Ninth Gate (Artisan) | $27,491,000 | $9,756,000 | $3,252,000 | Mar 10, 2000 |
| 95 | High Fidelity (Disney) | $40,197,000 | $9,471,000 | $3,157,000 | Mar 31, 2000 |
| 96 | Highlander: Endgame (Miramax / Dimension) | $18,873,000 | $9,168,000 | $3,056,000 | Sep 01, 2000 |
| 97 | Loser (Sony / Columbia) | $23,007,000 | $8,851,000 | $2,950,000 | Jul 21, 2000 |
| 98 | Eye of the Beholder (Destination) | $24,307,000 | $8,779,000 | $2,926,000 | Jan 28, 2000 |
| 99 | The Next Best Thing (Paramount) | $22,082,000 | $8,648,000 | $2,883,000 | Mar 03, 2000 |
| 100 | Wonder Boys (Paramount) | $28,568,000 | $8,557,000 | $2,852,000 | Feb 23, 2000 |
| 101 | Drowning Mona (Destination) | $22,842,000 | $8,547,000 | $2,849,000 | Mar 03, 2000 |
| 102 | The Little Vampire (New Line) | $19,994,000 | $8,426,000 | $2,809,000 | Oct 27, 2000 |
| 103 | Bait (Warner Bros.) | $22,576,000 | $8,081,000 | $2,694,000 | Sep 15, 2000 |
| 104 | The Ladies Man (Paramount) | $20,058,000 | $7,994,000 | $2,665,000 | Oct 13, 2000 |
| 105 | The Contender (DreamWorks) | $26,328,000 | $7,902,000 | $2,634,000 | Oct 13, 2000 |
| 106 | Ready to Rumble (Warner Bros.) | $18,259,000 | $7,745,000 | $2,582,000 | Apr 07, 2000 |
| 107 | Dr. T and the Women (Artisan) | $19,318,000 | $7,384,000 | $2,461,000 | Oct 12, 2000 |
| 108 | American Psycho (Lionsgate) | $22,200,000 | $7,308,000 | $2,436,000 | Apr 14, 2000 |
| 109 | All the Pretty Horses (Miramax) | $22,892,000 | $7,160,000 | $2,387,000 | Dec 25, 2000 |
| 110 | Center Stage (Sony / Columbia) | $25,337,000 | $6,783,000 | $2,261,000 | May 12, 2000 |
| 111 | Lucky Numbers (Paramount) | $14,793,000 | $6,683,000 | $2,228,000 | Oct 27, 2000 |
| 112 | Here on Earth (Fox) | $15,501,000 | $6,645,000 | $2,215,000 | Mar 15, 2000 |
| 113 | Godzilla 2000 (Sony / TriStar) | $14,786,000 | $6,493,000 | $2,164,000 | Aug 18, 2000 |
| 114 | Digimon: The Movie (Fox) | $14,188,000 | $6,236,000 | $2,079,000 | Oct 06, 2000 |
| 115 | Thomas and the Magic Railroad (Destination) | $23,472,000 | $6,121,000 | $2,040,000 | Jul 26, 2000 |
| 116 | Whatever It Takes (Sony / Columbia) | $12,883,000 | $6,046,000 | $2,015,000 | Mar 24, 2000 |
| 117 | The Crew (Disney) | $19,184,000 | $5,969,000 | $1,990,000 | Aug 25, 2000 |
| 118 | Small Time Crooks (DreamWorks) | $25,436,000 | $5,717,000 | $1,906,000 | May 19, 2000 |
| 119 | The Legend of Drunken Master (Miramax / Dimension) | $17,023,000 | $5,664,000 | $1,888,000 | Oct 20, 2000 |
| 120 | 3 Strikes (MGM) | $14,484,000 | $5,428,000 | $1,809,000 | Mar 03, 2000 |
| 121 | Screwed (Universal) | $10,352,000 | $4,921,000 | $1,640,000 | May 12, 2000 |
| 122 | What Planet Are You From? (Sony / Columbia) | $9,268,000 | $4,432,000 | $1,477,000 | Mar 03, 2000 |
| 123 | Whipped (Destination) | $6,127,000 | $4,021,000 | $1,340,000 | Sep 01, 2000 |
| 124 | Where the Money Is (USA Films) | $8,340,000 | $3,703,000 | $1,234,000 | Apr 14, 2000 |
| 125 | I Dreamed of Africa (Sony / Columbia) | $9,798,000 | $3,552,000 | $1,184,000 | May 05, 2000 |
| 126 | Gossip (Warner Bros.) | $7,525,000 | $3,420,000 | $1,140,000 | Apr 21, 2000 |
| 127 | Almost Famous (DreamWorks) | $47,927,000 | $3,410,000 | $1,137,000 | Sep 15, 2000 |
| 128 | Fantasia 2000 (Disney) | $89,352,000 | $3,374,000 | $1,125,000 | Jan 01, 2000 |
| 129 | Black and White (Sony / Columbia) | $7,774,000 | $3,259,000 | $1,086,000 | Apr 07, 2000 |
| 130 | The Way of the Gun (Artisan) | $8,921,000 | $3,169,000 | $1,056,000 | Sep 08, 2000 |
| 131 | Woman on Top (Fox Searchlight) | $7,395,000 | $2,958,000 | $986,000 | Sep 22, 2000 |
| 132 | Duets (Disney) | $6,982,000 | $2,950,000 | $983,000 | Sep 15, 2000 |
| 133 | Held Up (Trimark) | $6,932,000 | $2,815,000 | $938,000 | May 12, 2000 |
| 134 | Price of Glory (New Line) | $5,069,000 | $2,374,000 | $791,000 | Mar 31, 2000 |
| 135 | The In Crowd (Warner Bros.) | $7,779,000 | $2,218,000 | $739,000 | Jul 21, 2000 |
| 136 | Finding Forrester (Sony / Columbia) | $76,313,000 | $1,033,000 | $344,000 | Dec 22, 2000 |
| 137 | Crouching Tiger, Hidden Dragon (Sony Pictures Classics) | $188,672,000 | $975,000 | $325,000 | Dec 08, 2000 |
| 138 | State and Main (Fine Line) | $10,230,000 | $855,000 | $285,000 | Dec 22, 2000 |
| 139 | Michael Jordan to the Max (IMAX) | $27,475,000 | $852,000 | $284,000 | May 05, 2000 |
| 140 | Best in Show (Warner Bros.) | $27,570,000 | $609,000 | $203,000 | Sep 29, 2000 |
| 141 | Saving Grace (Fine Line) | $17,940,000 | $423,000 | $141,000 | Aug 04, 2000 |
| 142 | Cyberworld 3-D (IMAX) | $16,577,000 | $410,000 | $137,000 | Oct 06, 2000 |
| 143 | Quills (Fox Searchlight) | $10,408,000 | $367,000 | $122,000 | Nov 24, 2000 |
| 144 | The Virgin Suicides (Paramount Classics) | $7,227,000 | $346,000 | $115,000 | Apr 21, 2000 |
| 145 | Billy Elliot (Universal Focus) | $32,401,000 | $318,000 | $106,000 | Oct 13, 2000 |
| 146 | O Brother, Where Art Thou? (Disney) | $67,045,000 | $287,000 | $96,000 | Dec 22, 2000 |
| 147 | Chocolat (2000) (Miramax) | $105,340,000 | $232,000 | $77,000 | Dec 15, 2000 |
| 148 | Shadow of the Vampire (Lionsgate) | $12,217,000 | $221,000 | $74,000 | Dec 29, 2000 |
| 149 | You Can Count on Me (Paramount Classics) | $13,528,000 | $174,000 | $58,000 | Nov 10, 2000 |
| 150 | The Tao of Steve (Sony Classics) | $6,397,000 | $135,000 | $45,000 | Aug 04, 2000 |
| 151 | Dancer in the Dark (Fine Line) | $6,165,000 | $135,000 | $45,000 | Sep 22, 2000 |
| 152 | Before Night Falls (Fine Line) | $6,249,000 | $126,000 | $42,000 | Dec 22, 2000 |
| 153 | Requiem for a Dream (Artisan) | $5,356,000 | $95,000 | $32,000 | Oct 06, 2000 |
| 154 | Croupier (Shooting Gallery) | $9,136,000 | $94,000 | $31,000 | Apr 21, 2000 |
| 155 | Malèna (Miramax) | $5,079,000 | $92,000 | $31,000 | Dec 22, 2000 |
| 156 | My Dog Skip (Warner Bros.) | $50,284,000 | $84,000 | $28,000 | Jan 14, 2000 |
| 157 | East is East (Miramax) | $6,153,000 | $79,000 | $26,000 | Apr 14, 2000 |
| 158 | Cirque du Soleil: Journey of Man (Sony Pictures Classics) | $23,021,000 | $73,000 | $24,000 | May 05, 2000 |
| 159 | Pollock (Sony Pictures Classics) | $12,666,000 | $65,000 | $22,000 | Dec 15, 2000 |
| 160 | Snatch (Sony / Screen Gems) | $44,677,000 | $41,000 | $14,000 | Dec 08, 2000 |
| 161 | The Big Blue: Director's Cut (2000) (IDP) | $5,275,000 | $21,000 | $7,000 | Jul 14, 2000 |
| 162 | The Gift (Paramount Classics) | $17,690,000 | $17,000 | $6,000 | Dec 22, 2000 |
