| 1 | 21 And Over (Relativity Media) | $25,682,380 | $8,754,168 | $2,918,056 | Mar 01, 2013 |
| 2 | 42 (2013) (Warner Bros.) | $89,804,450 | $27,487,144 | $9,162,381 | Apr 12, 2013 |
| 3 | A Good Day to Die Hard (Fox) | $67,349,198 | $24,834,845 | $8,278,282 | Feb 14, 2013 |
| 4 | A Haunted House (Open Road) | $40,041,683 | $18,101,682 | $6,033,894 | Jan 11, 2013 |
| 5 | Admission (Focus) | $17,980,177 | $6,154,984 | $2,051,661 | Mar 22, 2013 |
| 6 | Beautiful Creatures (2013) (Warner Bros.) | $19,452,138 | $7,582,595 | $2,527,532 | Feb 14, 2013 |
| 7 | Broken City (Fox) | $19,701,164 | $8,268,908 | $2,756,303 | Jan 18, 2013 |
| 8 | Bullet to the Head (Warner Bros.) | $9,489,829 | $4,548,201 | $1,516,067 | Feb 01, 2013 |
| 9 | Dark Skies (Weinstein / Dimension) | $17,418,667 | $8,189,166 | $2,729,722 | Feb 22, 2013 |
| 10 | Dead Man Down (FilmDistrict) | $10,895,295 | $5,345,250 | $1,781,750 | Mar 08, 2013 |
| 11 | Escape From Planet Earth (Weinstein Company) | $55,703,341 | $15,891,055 | $5,297,018 | Feb 15, 2013 |
| 12 | Evil Dead (Sony / TriStar) | $54,036,283 | $25,775,847 | $8,591,949 | Apr 05, 2013 |
| 13 | G.I. Joe: Retaliation (Paramount) | $120,614,665 | $40,501,814 | $13,500,605 | Mar 28, 2013 |
| 14 | Gangster Squad (Warner Bros.) | $46,000,903 | $17,070,347 | $5,690,116 | Jan 11, 2013 |
| 15 | Hansel and Gretel: Witch Hunters (Paramount) | $55,703,475 | $19,690,956 | $6,563,652 | Jan 25, 2013 |
| 16 | Identity Thief (Universal) | $134,049,465 | $34,551,025 | $11,517,008 | Feb 08, 2013 |
| 17 | Iron Man 3 (Disney) | $348,082,524 | $174,144,585 | $58,048,195 | May 03, 2013 |
| 18 | Jack the Giant Slayer (Warner Bros. / New Line) | $64,861,701 | $27,202,226 | $9,067,409 | Mar 01, 2013 |
| 19 | Jurassic Park 3D (Universal) | $45,385,935 | $18,620,145 | $6,206,715 | Apr 05, 2013 |
| 20 | Mama (Universal) | $71,628,180 | $28,402,310 | $9,467,437 | Jan 18, 2013 |
| 21 | Movie 43 (Relativity Media) | $8,840,453 | $4,805,878 | $1,601,959 | Jan 25, 2013 |
| 22 | Mud (Roadside Attractions) | $12,607,297 | $2,215,891 | $738,630 | Apr 26, 2013 |
| 23 | Oblivion (2013) (Universal) | $86,465,165 | $37,054,485 | $12,351,495 | Apr 19, 2013 |
| 24 | Olympus Has Fallen (FilmDistrict) | $97,518,246 | $30,373,794 | $10,124,598 | Mar 22, 2013 |
| 25 | Oz: The Great and Powerful (Disney) | $231,563,051 | $79,110,453 | $26,370,151 | Mar 08, 2013 |
| 26 | Pain and Gain (Paramount) | $47,911,740 | $20,244,505 | $6,748,168 | Apr 26, 2013 |
| 27 | Parker (FilmDistrict) | $17,616,641 | $7,008,222 | $2,336,074 | Jan 25, 2013 |
| 28 | Quartet (Weinstein Company) | $18,209,942 | $47,122 | $15,707 | Jan 11, 2013 |
| 29 | Safe Haven (Relativity Media) | $71,339,127 | $21,401,594 | $7,133,865 | Feb 14, 2013 |
| 30 | Scary Movie 5 (Weinstein / Dimension) | $31,302,911 | $14,157,367 | $4,719,122 | Apr 12, 2013 |
| 31 | Side Effects (2013) (Open Road) | $32,172,757 | $9,303,145 | $3,101,048 | Feb 08, 2013 |
| 32 | Snitch (2013) (Lionsgate / Summit) | $42,872,913 | $13,167,607 | $4,389,202 | Feb 22, 2013 |
| 33 | Spring Breakers (A24) | $14,055,487 | $263,002 | $87,667 | Mar 15, 2013 |
| 34 | Star Trek Into Darkness (Paramount) | $108,827,288 | $70,165,559 | $23,388,520 | May 16, 2013 |
| 35 | Texas Chainsaw 3D (Lionsgate) | $34,341,945 | $21,744,470 | $7,248,157 | Jan 04, 2013 |
| 36 | The Big Wedding (Lionsgate) | $20,856,476 | $7,591,663 | $2,530,554 | Apr 26, 2013 |
| 37 | The Call (Sony / TriStar) | $51,319,362 | $17,118,745 | $5,706,248 | Mar 15, 2013 |
| 38 | The Croods (Fox / DreamWorks Animation) | $178,023,288 | $43,639,736 | $14,546,579 | Mar 22, 2013 |
| 39 | The Great Gatsby (2013) (Warner Bros.) | $100,726,891 | $50,085,184 | $16,695,061 | May 10, 2013 |
| 40 | The Host (2013) (Open Road) | $26,587,356 | $10,600,112 | $3,533,371 | Mar 29, 2013 |
| 41 | The Incredible Burt Wonderstone (Warner Bros. / New Line) | $22,537,881 | $10,177,257 | $3,392,419 | Mar 15, 2013 |
| 42 | The Last Exorcism Part II (CBS Films) | $15,179,303 | $7,728,354 | $2,576,118 | Mar 01, 2013 |
| 43 | The Last Stand (Lionsgate) | $12,050,299 | $6,281,433 | $2,093,811 | Jan 18, 2013 |
| 44 | The Place Beyond the Pines (Focus) | $20,794,827 | $279,457 | $93,152 | Mar 29, 2013 |
| 45 | Tyler Perry Presents Peeples (Lionsgate) | $8,476,365 | $4,611,534 | $1,537,178 | May 10, 2013 |
| 46 | Tyler Perry's Temptation (Lionsgate) | $51,876,292 | $21,641,679 | $7,213,893 | Mar 29, 2013 |
| 47 | Warm Bodies (Lionsgate / Summit) | $66,380,662 | $20,353,967 | $6,784,656 | Feb 01, 2013 |
