| 1 | Clash of the Titans (2010) (Warner Bros.) | Apr 02 - Apr 04, 2010 | $61,235,105 | 3,777 | $16,213 | 1 |
| 2 | G.I. Joe: Retaliation (Paramount) | Mar 29 - Mar 31, 2013 | $40,501,814 | 3,719 | $10,891 | 1 |
| 3 | Scary Movie 4 (Weinstein / Dimension) | Apr 14 - Apr 16, 2006 | $40,223,099 | 3,602 | $11,167 | 1 |
| 4 | The Hunger Games (Lionsgate) | Apr 06 - Apr 08, 2012 | $33,111,557 | 4,137 | $8,004 | 3 |
| 5 | Hannah Montana: The Movie (Disney) | Apr 10 - Apr 12, 2009 | $32,323,405 | 3,118 | $10,367 | 1 |
| 6 | Panic Room (Sony / Columbia) | Mar 29 - Mar 31, 2002 | $30,057,871 | 3,053 | $9,845 | 1 |
| 7 | Tyler Perry's Why Did I Get Married Too? (Lionsgate) | Apr 02 - Apr 04, 2010 | $29,289,537 | 2,155 | $13,591 | 1 |
| 8 | How to Train Your Dragon (Paramount / DreamWorks) | Apr 02 - Apr 04, 2010 | $29,010,044 | 4,060 | $7,145 | 2 |
| 9 | The Matrix (Warner Bros.) | Apr 02 - Apr 04, 1999 | $27,789,545 | 2,849 | $9,754 | 1 |
| 10 | Fast & Furious (Universal) | Apr 10 - Apr 12, 2009 | $27,237,153 | 3,472 | $7,845 | 2 |
| 11 | The Croods (Fox / DreamWorks Animation) | Mar 29 - Mar 31, 2013 | $26,705,868 | 4,065 | $6,570 | 2 |
| 12 | Rio (2011) (Fox) | Apr 22 - Apr 24, 2011 | $26,323,321 | 3,842 | $6,851 | 2 |
| 13 | Liar Liar (Universal) | Mar 28 - Mar 30, 1997 | $25,377,308 | 2,853 | $8,895 | 2 |
| 14 | Tyler Perry's Madea's Big Happy Family (Lionsgate) | Apr 22 - Apr 24, 2011 | $25,068,677 | 2,288 | $10,957 | 1 |
| 15 | Anger Management (Sony / Columbia) | Apr 18 - Apr 20, 2003 | $25,005,769 | 3,570 | $7,004 | 2 |
| 16 | Dr. Seuss' Horton Hears a Who! (Fox) | Mar 21 - Mar 23, 2008 | $24,589,679 | 3,961 | $6,208 | 2 |
| 17 | Blades of Glory (Paramount / DreamWorks) | Apr 06 - Apr 08, 2007 | $22,523,561 | 3,410 | $6,605 | 2 |
| 18 | Monsters vs. Aliens (Paramount / DreamWorks) | Apr 10 - Apr 12, 2009 | $21,811,941 | 4,136 | $5,274 | 3 |
| 19 | Tyler Perry's Temptation (Lionsgate) | Mar 29 - Mar 31, 2013 | $21,641,679 | 2,047 | $10,572 | 1 |
| 20 | American Reunion (Universal) | Apr 06 - Apr 08, 2012 | $21,514,080 | 3,192 | $6,740 | 1 |
| 21 | Guess Who (Sony / Columbia) | Mar 25 - Mar 27, 2005 | $20,671,177 | 3,147 | $6,569 | 1 |
| 22 | Tyler Perry's Meet the Browns (Lionsgate) | Mar 21 - Mar 23, 2008 | $20,083,162 | 2,006 | $10,012 | 1 |
| 23 | Ice Age: The Meltdown (Fox) | Apr 14 - Apr 16, 2006 | $20,027,101 | 3,873 | $5,171 | 3 |
| 24 | U-571 (Universal) | Apr 21 - Apr 23, 2000 | $19,553,682 | 2,583 | $7,570 | 1 |
| 25 | Indecent Proposal (Paramount) | Apr 09 - Apr 11, 1993 | $18,387,632 | 1,694 | $10,855 | 1 |
| 26 | Ice Age (Fox) | Mar 29 - Mar 31, 2002 | $18,135,784 | 3,333 | $5,441 | 3 |
| 27 | Titanic 3D (Paramount) | Apr 06 - Apr 08, 2012 | $17,285,453 | 2,674 | $6,464 | 1 |
| 28 | Water for Elephants (Fox) | Apr 22 - Apr 24, 2011 | $16,842,353 | 2,817 | $5,979 | 1 |
| 29 | Meet the Robinsons (Disney) | Apr 06 - Apr 08, 2007 | $16,716,162 | 3,435 | $4,866 | 2 |
| 30 | Holes (Disney) | Apr 18 - Apr 20, 2003 | $16,300,170 | 2,331 | $6,993 | 1 |
| 31 | The Rookie (2002) (Disney) | Mar 29 - Mar 31, 2002 | $16,022,324 | 2,511 | $6,381 | 1 |
| 32 | The Last Song (Disney) | Apr 02 - Apr 04, 2010 | $16,007,426 | 2,673 | $5,989 | 1 |
| 33 | City of Angels (Warner Bros.) | Apr 10 - Apr 12, 1998 | $15,369,048 | 2,212 | $6,948 | 1 |
| 34 | The Passion of the Christ (Newmarket) | Apr 09 - Apr 11, 2004 | $15,217,730 | 3,240 | $4,697 | 7 |
| 35 | Wrath of the Titans (Warner Bros.) | Apr 06 - Apr 08, 2012 | $14,732,121 | 3,545 | $4,156 | 2 |
| 36 | The Devil's Own (Sony / Columbia) | Mar 28 - Mar 30, 1997 | $14,274,503 | 2,504 | $5,701 | 1 |
| 37 | Are We Done Yet? (Sony / Columbia) | Apr 06 - Apr 08, 2007 | $14,262,318 | 2,877 | $4,957 | 1 |
| 38 | Olympus Has Fallen (FilmDistrict) | Mar 29 - Mar 31, 2013 | $14,147,416 | 3,106 | $4,555 | 2 |
| 39 | Teenage Mutant Ninja Turtles (1990) (New Line) | Apr 13 - Apr 15, 1990 | $14,064,921 | 2,377 | $5,917 | 3 |
| 40 | Miss Congeniality 2: Armed and Fabulous (Warner Bros.) | Mar 25 - Mar 27, 2005 | $14,042,766 | 3,233 | $4,344 | 1 |
| 41 | The Ring Two (DreamWorks) | Mar 25 - Mar 27, 2005 | $13,616,901 | 3,341 | $4,076 | 2 |
| 42 | Lost in Space (New Line) | Apr 10 - Apr 12, 1998 | $13,395,392 | 3,306 | $4,052 | 2 |
| 43 | Teenage Mutant Ninja Turtles II (New Line) | Mar 29 - Mar 31, 1991 | $13,049,622 | 2,868 | $4,550 | 2 |
| 44 | Blade II (New Line) | Mar 29 - Mar 31, 2002 | $13,022,515 | 2,707 | $4,811 | 2 |
| 45 | Robots (Fox) | Mar 25 - Mar 27, 2005 | $12,915,013 | 3,431 | $3,764 | 3 |
| 46 | Malibu's Most Wanted (Warner Bros.) | Apr 18 - Apr 20, 2003 | $12,618,979 | 2,503 | $5,042 | 1 |
| 47 | Spy Kids (Miramax / Dimension) | Apr 13 - Apr 15, 2001 | $12,501,512 | 3,172 | $3,941 | 3 |
| 48 | HOP (Universal) | Apr 22 - Apr 24, 2011 | $12,185,905 | 3,616 | $3,370 | 4 |
| 49 | Oz: The Great and Powerful (Disney) | Mar 29 - Mar 31, 2013 | $11,702,316 | 3,324 | $3,521 | 4 |
| 50 | Grindhouse (Weinstein / Dimension) | Apr 06 - Apr 08, 2007 | $11,596,352 | 2,624 | $4,419 | 1 |
