| 1 | Alien³ (Fox) | May 22 - May 24, 1992 | $19,449,429 | 2,227 | $8,733 | 1 |
| 2 | Angels & Demons (Sony / Columbia) | May 22 - May 24, 2009 | $21,721,947 | 3,527 | $6,159 | 2 |
| 3 | Back to the Future Part III (Universal) | May 25 - May 27, 1990 | $19,087,635 | 2,019 | $9,454 | 1 |
| 4 | Beverly Hills Cop II (Paramount) | May 22 - May 24, 1987 | $26,348,818 | 2,326 | $11,328 | 1 |
| 5 | Bruce Almighty (Universal) | May 23 - May 25, 2003 | $67,953,911 | 3,483 | $19,510 | 1 |
| 6 | Crocodile Dundee II (Paramount) | May 27 - May 29, 1988 | $19,801,200 | 2,837 | $6,980 | 1 |
| 7 | Dinosaur (Disney) | May 26 - May 28, 2000 | $25,037,914 | 3,302 | $7,583 | 2 |
| 8 | Godzilla (1998) (Sony / TriStar) | May 22 - May 24, 1998 | $44,048,282 | 3,310 | $13,308 | 1 |
| 9 | Indiana Jones and the Kingdom of the Crystal Skull (Paramount) | May 23 - May 25, 2008 | $100,137,761 | 4,260 | $23,507 | 1 |
| 10 | Indiana Jones and the Last Crusade (Paramount) | May 26 - May 28, 1989 | $29,356,267 | 2,327 | $12,615 | 1 |
| 11 | Indiana Jones and the Temple of Doom (Paramount) | May 25 - May 27, 1984 | $25,336,915 | 1,687 | $15,019 | 1 |
| 12 | Insomnia (2002) (Warner Bros.) | May 24 - May 26, 2002 | $20,930,454 | 2,610 | $8,019 | 1 |
| 13 | Iron Man (Paramount) | May 23 - May 25, 2008 | $20,447,661 | 3,915 | $5,223 | 4 |
| 14 | Kung Fu Panda 2 (Paramount / DreamWorks) | May 27 - May 29, 2011 | $47,656,302 | 3,925 | $12,142 | 1 |
| 15 | Lethal Weapon 3 (Warner Bros.) | May 22 - May 24, 1992 | $22,375,410 | 2,510 | $8,915 | 2 |
| 16 | Madagascar (DreamWorks) | May 27 - May 29, 2005 | $47,223,568 | 4,131 | $11,432 | 1 |
| 17 | Marvel's The Avengers (Disney) | May 25 - May 27, 2012 | $36,686,871 | 3,918 | $9,364 | 4 |
| 18 | Men in Black 3 (Sony / Columbia) | May 25 - May 27, 2012 | $54,592,779 | 4,248 | $12,851 | 1 |
| 19 | Mission: Impossible (Paramount) | May 24 - May 26, 1996 | $45,436,479 | 3,012 | $15,085 | 1 |
| 20 | Mission: Impossible II (Paramount) | May 26 - May 28, 2000 | $57,845,902 | 3,653 | $15,835 | 1 |
| 21 | Night at the Museum: Battle of the Smithsonian (Fox) | May 22 - May 24, 2009 | $54,172,744 | 4,096 | $13,226 | 1 |
| 22 | Notting Hill (Universal) | May 28 - May 30, 1999 | $21,811,389 | 2,747 | $7,940 | 1 |
| 23 | Over the Hedge (Paramount / DreamWorks) | May 26 - May 28, 2006 | $27,064,201 | 4,093 | $6,612 | 2 |
| 24 | Pearl Harbor (Disney) | May 25 - May 27, 2001 | $59,078,293 | 3,214 | $18,382 | 1 |
| 25 | Pirates of the Caribbean: At World's End (Disney) | May 25 - May 27, 2007 | $114,733,683 | 4,362 | $26,303 | 1 |
| 26 | Pirates of the Caribbean: On Stranger Tides (Disney) | May 27 - May 29, 2011 | $39,828,974 | 4,164 | $9,565 | 2 |
| 27 | Prince of Persia: The Sands of Time (Disney) | May 28 - May 30, 2010 | $30,095,259 | 3,646 | $8,254 | 1 |
| 28 | Rambo: First Blood Part II (TriStar) | May 24 - May 26, 1985 | $20,177,639 | 2,074 | $9,729 | 1 |
| 29 | Return of the Jedi (Fox) | May 27 - May 29, 1983 | $23,020,855 | 1,002 | $22,975 | 1 |
| 30 | Sex and the City 2 (Warner Bros. / New Line) | May 28 - May 30, 2010 | $31,002,000 | 3,445 | $8,999 | 1 |
| 31 | Shrek (DreamWorks) | May 25 - May 27, 2001 | $42,481,295 | 3,623 | $11,725 | 2 |
| 32 | Shrek 2 (DreamWorks) | May 28 - May 30, 2004 | $72,172,419 | 4,223 | $17,090 | 2 |
| 33 | Shrek Forever After (Paramount / DreamWorks) | May 28 - May 30, 2010 | $43,311,063 | 4,367 | $9,918 | 2 |
| 34 | Shrek the Third (Paramount / DreamWorks) | May 25 - May 27, 2007 | $53,040,872 | 4,172 | $12,714 | 2 |
| 35 | Spider-Man (Sony / Columbia) | May 24 - May 26, 2002 | $28,509,482 | 3,876 | $7,355 | 4 |
| 36 | Star Trek (Paramount) | May 22 - May 24, 2009 | $22,892,687 | 4,053 | $5,648 | 3 |
| 37 | Star Wars: Episode I - The Phantom Menace (Fox) | May 28 - May 30, 1999 | $51,399,425 | 3,023 | $17,003 | 2 |
| 38 | Star Wars: Episode II - Attack of the Clones (Fox) | May 24 - May 26, 2002 | $47,879,771 | 3,161 | $15,147 | 2 |
| 39 | Star Wars: Episode III - Revenge of the Sith (Fox) | May 27 - May 29, 2005 | $55,205,734 | 3,663 | $15,071 | 2 |
| 40 | Terminator Salvation (Warner Bros.) | May 22 - May 24, 2009 | $42,558,199 | 3,530 | $12,056 | 1 |
| 41 | The Chronicles of Narnia: Prince Caspian (Disney) | May 23 - May 25, 2008 | $22,794,214 | 3,929 | $5,802 | 2 |
| 42 | The Da Vinci Code (Sony / Columbia) | May 26 - May 28, 2006 | $34,032,154 | 3,754 | $9,066 | 2 |
| 43 | The Day After Tomorrow (Fox) | May 28 - May 30, 2004 | $68,743,973 | 3,425 | $20,071 | 1 |
| 44 | The Flintstones (Universal) | May 27 - May 29, 1994 | $29,688,904 | 2,498 | $11,885 | 1 |
| 45 | The Hangover Part II (Warner Bros.) | May 27 - May 29, 2011 | $85,946,294 | 3,615 | $23,775 | 1 |
| 46 | The Longest Yard (2005) (Paramount) | May 27 - May 29, 2005 | $47,607,501 | 3,634 | $13,101 | 1 |
| 47 | The Lost World: Jurassic Park (Universal) | May 23 - May 25, 1997 | $72,132,275 | 3,281 | $21,985 | 1 |
| 48 | The Matrix Reloaded (Warner Bros.) | May 23 - May 25, 2003 | $36,904,917 | 3,603 | $10,243 | 2 |
| 49 | Twister (1996) (Warner Bros.) | May 24 - May 26, 1996 | $29,645,430 | 2,808 | $10,557 | 3 |
| 50 | X-Men: The Last Stand (Fox) | May 26 - May 28, 2006 | $102,750,291 | 3,690 | $27,846 | 1 |
